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中文名稱： 兔抗RPS6KA1(Phospho-Thr573) 多克隆抗體
英文名稱： Anti-RPS6KA1(Phospho-Thr573) rabbit polyclonal antibody
別 名： RSK; HU-1; RSK1; MAPKAPK1A
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： RPS6KA1(Phospho-Thr573)
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes. |
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Applications: |
WB, IHC |
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Name of antibody: |
RPS6KA1(Phospho-Thr573) |
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Immunogen: |
Peptide sequence around phosphorylation site of threonine 573(L-M-T(p)-P-C) derived from Human p90 RSK. |
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Full name: |
ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
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Synonyms： |
RSK; HU-1; RSK1; MAPKAPK1A |
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SwissProt: |
Q15418 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
83 kDa |
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WB Positive control: |
293 cells lysates treated with UV |
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WB Recommended dilution: |
500-1000 |
