購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. |
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Applications: |
WB, IF |
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Name of antibody: |
SIRT2 |
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Immunogen: |
Fusion protein of human SIRT2 |
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Full name: |
sirtuin 2 |
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Synonyms: |
SIR2; SIR2L; SIR2L2 |
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SwissProt: |
Q8IXJ6 |
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WB Predicted band size: |
43 kDa |
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WB Positive control: |
PC-12 cell, Rat Brain tissue and Mouse Brain tissue lysates |
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WB Recommended dilution: |
1000-5000 |
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IF positive control: |
Hela cells |
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IF Recommend dilution: |
25-50 |
