購(gòu)物車(chē)
幫助
021-54845833/15800441009
技術(shù)規(guī)格
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Background: |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |
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Applications: |
WB, IP |
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Name of antibody: |
SIRT1 |
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Immunogen: |
Fusion protein of human SIRT1 |
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Full name: |
sirtuin 1 |
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Synonyms: |
SIR2; SIR2L1; SIR2alpha |
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SwissProt: |
Q96EB6 |
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WB Predicted band size: |
82 kDa |
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WB Positive control: |
CEM, A549, Ramos, Jurkat and Hela cell lysates |
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WB Recommended dilution: |
1000-5000 |
