購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗ABCD1多克隆抗體
英文名稱： Anti-ABCD1 rabbit polyclonal antibody
別 名： ALD; AMN; ALDP; ABC42
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
抗 原： ABCD1
宿 主： Rabbit
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ABCD1 |
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Immunogen: |
Synthetic peptide of human ABCD1 |
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Full name: |
ATP binding cassette subfamily D member 1 |
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Synonyms: |
ALD; AMN; ALDP; ABC42 |
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SwissProt: |
P33897 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer and human tonsil |
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IHC Recommend dilution: |
60-450 |
