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  • SELENOF 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW4813
    • 應用 : 僅供科研使用
    • 貨期 : 現貨
    • 規格 :1mg/100ug
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中文名稱: SELENOF 抗原(重組蛋白)

英文名稱: SELENOF Antigen (Recombinant Protein)

別     名: selenoprotein F; SEP15

相關類別: 抗原

儲      存: 冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 97-165 amino acids of human SELENOF

技術規格

Full name:

selenoprotein F

Synonyms:

SEP15

Swissprot:

O60613

Gene Accession:

BC005294

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.


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