中文名稱：兔抗STRADA多克隆抗體

英文名稱： Anti-STRADA rabbit polyclonal antibody

別名： LYK5; PMSE; Stlk; STRAD; NY-BR-96

抗原： STRADA

儲存： 冷凍（-20℃）

宿主： Rabbit

相關(guān)類別：一抗

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.

Applications:

ELISA, IHC

Name of antibody:

STRADA

Immunogen:

Full length fusion protein

Full name:

STE20-related kinase adaptor alpha

Synonyms:

LYK5; PMSE; Stlk; STRAD; NY-BR-96

SwissProt:

Q7RTN6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and human gastric cancer

IHC Recommend dilution:

30-150

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兔抗STRADA多克隆抗體

Background:	The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.
Applications:	ELISA, IHC
Name of antibody:	STRADA
Immunogen:	Full length fusion protein
Full name:	STE20-related kinase adaptor alpha
Synonyms:	LYK5; PMSE; Stlk; STRAD; NY-BR-96
SwissProt:	Q7RTN6
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human esophagus cancer and human gastric cancer
IHC Recommend dilution:	30-150