中文名稱：兔抗SMAD2(Ab-465) 多克隆抗體

英文名稱： Anti-SMAD2(Ab-465) rabbit polyclonal antibody

別名： JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2

儲存： 冷凍（-20℃）避光

抗原： SMAD2(Ab-465)

宿主： Rabbit

反應種屬： Human

相關類別：一抗

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術規格

Background:

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

Applications:

WB

Name of antibody:

SMAD2(Ab-465)

Immunogen:

Synthesized peptide derived from C-terminal of human Smad2.

Full name:

SMAD family member 2

Synonyms：

JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2

SwissProt:

Q15796

WB Predicted band size:

52 kDa

WB Positive control:

293 cells, JurKat cells, HepG2 cells and K562 cells lysates

WB Recommended dilution:

500-3000

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兔抗SMAD2(Ab-465) 多克隆抗體

Background:	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Applications:	WB
Name of antibody:	SMAD2(Ab-465)
Immunogen:	Synthesized peptide derived from C-terminal of human Smad2.
Full name:	SMAD family member 2
Synonyms：	JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2
SwissProt:	Q15796
WB Predicted band size:	52 kDa
WB Positive control:	293 cells, JurKat cells, HepG2 cells and K562 cells lysates
WB Recommended dilution:	500-3000