中文名稱：兔抗MADD多克隆抗體

英文名稱： Anti-MADD rabbit polyclonal antibody

別名： DENN; IG20; RAB3GEP

相關(guān)類別：一抗

儲存： 冷凍（-20℃）避光

抗原： MADD

宿主： Rabbit

反應(yīng)種屬： Human Mouse Rat

標(biāo) 記物： Unconjugate

克隆類型： Unconjugate

技術(shù)規(guī)格

Background:

Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.

Applications:

WB, IHC, IF

Name of antibody:

MADD

Immunogen:

Synthesized peptide derived from internal of human MADD.

Full name:

MAP-kinase activating death domain

Synonyms：

DENN; IG20; RAB3GEP

SwissProt:

Q8WXG6

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

183 kDa

WB Positive control:

COLO cells, Hela cells and Jurkat cells lysates

WB Recommended dilution:

500-3000

IF positive control:

A549 cells

IF Recommend dilution:

100-500

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兔抗MADD多克隆抗體

Background:	Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.
Applications:	WB, IHC, IF
Name of antibody:	MADD
Immunogen:	Synthesized peptide derived from internal of human MADD.
Full name:	MAP-kinase activating death domain
Synonyms：	DENN; IG20; RAB3GEP
SwissProt:	Q8WXG6
IHC positive control:	Human brain tissue
IHC Recommend dilution:	50-100
WB Predicted band size:	183 kDa
WB Positive control:	COLO cells, Hela cells and Jurkat cells lysates
WB Recommended dilution:	500-3000
IF positive control:	A549 cells
IF Recommend dilution:	100-500