中文名稱(chēng)：兔抗GSDMA多克隆抗體

英文名稱(chēng)： Anti-GSDMA rabbit polyclonal antibody

別名： gasdermin A; GSDM; FKSG9; GSDM1

相關(guān)類(lèi)別：一抗

儲(chǔ) 存： 冷凍（-20℃）

宿主： Rabbit

抗原： GSDMA

反應(yīng)種屬： Human, Mouse

標(biāo) 記物： Unconjugate

克隆類(lèi)型： rabbit polyclonal

技術(shù)規(guī)格

Background:

May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).

Applications:

ELISA, WB, IHC

Name of antibody:

GSDMA

Immunogen:

Fusion protein of human GSDMA

Full name:

gasdermin A

Synonyms:

GSDM; FKSG9; GSDM1

SwissProt:

Q96QA5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human ovarian cancer

IHC Recommend dilution:

100-200

WB Predicted band size:

49 kDa

WB Positive control:

LO2 and 293T cell lysates

WB Recommended dilution:

500-2000

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兔抗GSDMA多克隆抗體

Background:	May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).
Applications:	ELISA, WB, IHC
Name of antibody:	GSDMA
Immunogen:	Fusion protein of human GSDMA
Full name:	gasdermin A
Synonyms:	GSDM; FKSG9; GSDM1
SwissProt:	Q96QA5
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human colorectal cancer and Human ovarian cancer
IHC Recommend dilution:	100-200
WB Predicted band size:	49 kDa
WB Positive control:	LO2 and 293T cell lysates
WB Recommended dilution:	500-2000