購(gòu)物車
幫助
021-54845833/15800441009
Background:
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).
Applications:
ELISA, IHC
Name of antibody:
USP5
Immunogen:
Fusion protein of human USP5
Full name:
ubiquitin specific peptidase 5 (isopeptidase T)
Synonyms：
ISOT
SwissProt:
P45974
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human thyroid cancer and Human esophagus cancer
IHC Recommend dilution:
25-100
