購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗UPF1多克隆抗體
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Background: |
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
UPF1 |
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Immunogen: |
Synthetic peptide of human UPF1 |
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Full name: |
UPF1 RNA helicase and ATPase |
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Synonyms: |
HUPF1; NORF1; RENT1; smg-2; pNORF1 |
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SwissProt: |
Q92900 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human liver cancer and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
124 kDa |
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WB Positive control: |
Raji cells |
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WB Recommended dilution: |
200-1000 |
