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中文名稱： 兔抗PAK1 (Phospho-Thr212)多克隆抗體
英文名稱： Anti-PAK1 (Phospho-Thr212) rabbit polyclonal antibody
別 名： PAKalpha
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： PAK1 (Phospho-Thr212)
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
PAK1 (Phospho-Thr212) |
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Immunogen: |
Synthetic peptide of human PAK1 (Phospho-Thr212) |
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Full name: |
p21 protein (Cdc42/Rac)-activated kinase 1 (Phospho-Thr212) |
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Synonyms： |
PAKalpha |
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SwissProt: |
Q13153 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
68 kDa |
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WB Positive control: |
293 cells untreated or treated with forskolin |
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WB Recommended dilution: |
500-1000 |
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IF Positive control: |
Hela cells |
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IF Recommended dilution |
100-200 |
