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中文名稱：兔抗SELPLG多克隆抗體
英文名稱： Anti-SELPLG rabbit polyclonal antibody
別 名： CLA; CD162; PSGL1; PSGL-1
儲 存： 冷凍（-20℃）
抗 原： SELPLG
宿 主： Rabbit
相關(guān)類別： 一抗
反應(yīng)種屬： Human
標(biāo)記物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SELPLG |
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Immunogen: |
Fusion protein of human SELPLG |
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Full name: |
selectin P ligand |
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Synonyms： |
CLA; CD162; PSGL1; PSGL-1 |
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SwissProt: |
Q14242 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
