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021-54845833/15800441009
中文名稱：兔抗SDHB多克隆抗體
英文名稱： Anti-SDHB rabbit polyclonal antibody
別 名： IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： SDHB
反應(yīng)種屬： Human, Mouse, Rat
標(biāo)記物： Unconjugate
克隆類型： rabbit polyclonal
Background:
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Applications:
ELISA, WB, IHC
Name of antibody:
SDHB
Immunogen:
Synthetic peptide of human SDHB
Full name:
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Synonyms：
IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP
SwissProt:
P21912
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human thyroid cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
32 kDa
WB Positive control:
293T cells and mouse brain tissue, human fetal liver tissue and hepg2 cells, Jurkat cells
WB Recommended dilution:
500-2000
技術(shù)規(guī)格
