購物車
幫助
021-54845833/15800441009
中文名稱：兔抗ROCK2多克隆抗體
英文名稱： Anti-ROCK2 rabbit polyclonal antibody
別 名： ROCK-II
抗 原： ROCK2
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
相關(guān)類別： 一抗
反應(yīng)種屬： Human, Mouse, Rat
標(biāo)記物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
ROCK2 |
|
Immunogen: |
Fusion protein of human ROCK2 |
|
Full name: |
Rho-associated, coiled-coil containing protein kinase 2 |
|
Synonyms： |
ROCK-II |
|
SwissProt: |
O75116 |
|
ELISA Recommended dilution: |
2000-5000 |
|
IHC positive control: |
Human cervical cancer and human ovarian cancer |
|
IHC Recommend dilution: |
25-100 |
