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中文名稱： 兔抗MYH11多克隆抗體
英文名稱： Anti-MYH11 rabbit polyclonal antibody
別 名： AAT4, FAA4, SMHC, SMMHC
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MYH11
反應(yīng)種屬： Human, Mouse, Rat
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MYH11 |
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Immunogen: |
Synthetic peptide of human MYH11 |
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Full name: |
Myosin, heavy chain 11, smooth muscle |
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Synonyms： |
AAT4, FAA4, SMHC, SMMHC |
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SwissProt: |
P35749 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human brain and Human cervical cancer |
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IHC Recommend dilution: |
50-200 |
