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021-54845833/15800441009
中文名稱： 兔抗MTA2多克隆抗體
英文名稱： Anti-MTA2 rabbit polyclonal antibody
別 名： PID; MTA1L1
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MTA2
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
MTA2 |
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Immunogen: |
Synthetic peptide of human MTA2 |
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Full name: |
metastasis associated 1 family member 2 |
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Synonyms: |
PID; MTA1L1 |
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SwissProt: |
O94776 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human lung cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
75 kDa |
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WB Positive control: |
NIH/3T3，A431，293T and Hela cell lysates |
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WB Recommended dilution: |
500-2000 |
