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中文名稱： 兔抗MLANA多克隆抗體
英文名稱： Anti-MLANA rabbit polyclonal antibody
別 名： MART1; MART-1
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MLANA
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Melan-A (also designated MART-1) is a melanocyte differentiation antigen that is specific to melanomas, melanocyte cell lines and retina. Melan-A peptide is recognized by most HLA-A2-restricted tumor-specific tumor-infiltrating lymphocytes in patients with melanoma. Antimelanoma cytotoxic T lymphocytes can be generated with a Melan-A peptide, implicating Melan-A as a potential candidate for antigen-specific immunotherapy in melanoma patients. Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MLANA |
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Immunogen: |
Synthetic peptide of human MLANA |
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Full name: |
melan-A |
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Synonyms: |
MART1; MART-1 |
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SwissProt: |
Q16655 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer |
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IHC Recommend dilution: |
40-250 |
