購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：SF3B3抗原（重組蛋白）
英文名稱： SF3B3 Antigen (Recombinant Protein)
別 名： RSE1; SAP130; SF3b130; STAF130
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 1008-1207 amino acids of human SF3B3 |
|
Full name: |
splicing factor 3b subunit 3 |
|
Synonyms: |
RSE1; SAP130; SF3b130; STAF130 |
|
Swissprot: |
Q15393 |
|
Gene Accession: |
BC000463 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. |
