購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： MCPH1 抗原（重組蛋白）
英文名稱(chēng)： MCPH1 Antigen (Recombinant Protein)
別 名： microcephalin 1; MCT; BRIT1
相關(guān)類(lèi)別： 抗原
儲(chǔ) 存： 冷凍（-20℃）
概 述
|
Fusion protein corresponding to a region derived from 363-562 amino acids of human MCPH1 |
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Full name: |
microcephalin 1 |
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Synonyms: |
MCT; BRIT1 |
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Swissprot: |
Q8NEM0 |
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Gene Accession: |
BC030702 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. |
