Name: PCMT1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： PCMT1抗原（重組蛋白）

英文名稱： PCMT1 Antigen (Recombinant Protein)

別名： protein-L-isoaspartate (D-aspartate) O-methyltransferase; PIMT

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 1-227 amino acids of human PCMT1

技術規格

Full name:	protein-L-isoaspartate (D-aspartate) O-methyltransferase
Synonyms:	PIMT
Swissprot:	P22061
Gene Accession:	BC007501
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

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