Name: NFKBID抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：NFKBID抗原（重組蛋白）

英文名稱： NFKBID Antigen (Recombinant Protein)

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 1-221 amino acids of human NFKBID

技術(shù)規(guī)格

Full name:	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
Synonyms:	TA-NFKBH, IkappaBNS
Swissprot:	Q8NI38
Gene Accession:	BC006273
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

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