Name: TIMP2 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：TIMP2 抗原（重組蛋白）

英文名稱： TIMP2 Antigen (Recombinant Protein)

別名： TIMP metallopeptidase inhibitor 2; CSC-21K

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 30-220 amino acids of human TIMP2

技術(shù)規(guī)格：

Full name:	TIMP metallopeptidase inhibitor 2
Synonyms:	CSC-21K
Swissprot:	P16035
Gene Accession:	BC052605
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

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