購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：PITX2抗原（重組蛋白）
英文名稱(chēng)： PITX2 Antigen (Recombinant Protein)
別 名： RS; RGS; ARP1; Brx1; IDG2; IGDS; IHG2; PTX2; RIEG; IGDS2; IRID2; Otlx2; RIEG1
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類(lèi)別： 抗原
概 述：
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Fusion protein corresponding to N terminal 285 amino acids of human PITX2 |
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Full name: |
paired-like homeodomain 2 |
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Synonyms: |
RS; RGS; ARP1; Brx1; IDG2; IGDS; IHG2; PTX2; RIEG; IGDS2; IRID2; Otlx2; RIEG1 |
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Swissprot: |
Q99697 |
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Gene Accession: |
BC013998 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
