Name: IKZF3抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：IKZF3抗原（重組蛋白）

英文名稱： IKZF3 Antigen (Recombinant Protein)

別名： AIO; AIOLOS; ZNFN1A3

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to C terminal 250 amino acids of human IKZF3

技術(shù)規(guī)格：

Full name:	IKAROS family zinc finger 3 (Aiolos)
Synonyms:	AIO; AIOLOS; ZNFN1A3
Swissprot:	Q9UKT9
Gene Accession:	BC032707
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

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