Name: EIF3H抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)： EIF3H抗原（重組蛋白）

英文名稱(chēng)： EIF3H Antigen (Recombinant Protein)

別名： EIF3S3; eIF3-p40; eIF3-gamma

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概述：

Fusion protein corresponding to C terminal 300 amino acids of human EIF3H

技術(shù)規(guī)格：

Full name:	eukaryotic translation initiation factor 3, subunit H
Synonyms:	EIF3S3; eIF3-p40; eIF3-gamma
Swissprot:	O15372
Gene Accession:	BC000386
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Eukaryotic translation initiation factor 3 subunit H is a protein that in humans is encoded by the EIF3H gene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

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