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021-54845833/15800441009
中文名稱： BMX抗原（重組蛋白）
英文名稱： BMX Antigen (Recombinant Protein)
別 名： ETK; PSCTK2; PSCTK3
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述：
|
Fusion protein corresponding to C terminal 219 amino acids of human BMX |
技術規格：
|
Full name: |
BMX non-receptor tyrosine kinase |
|
Synonyms: |
ETK; PSCTK2; PSCTK3 |
|
Swissprot: |
P51813 |
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Gene Accession: |
BC016652 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
