Name: DAND5抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： DAND5抗原（重組蛋白）

英文名稱： DAND5 Antigen (Recombinant Protein)

別名： SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:	DAN domain family member 5, BMP antagonist
Synonyms:	SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3
Swissprot:	Q8N907
Gene Accession:	BC113476
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

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