Name: CHMP2B 抗原（重組蛋白
Brand: 通蔚生物

中文名稱： CHMP2B 抗原（重組蛋白）

英文名稱： CHMP2B Antigen (Recombinant Protein)

別名： charged multivesicular body protein 2B; DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 94-213 amino acids of human CHMP2B

技術(shù)規(guī)格

Full name:	charged multivesicular body protein 2B
Synonyms:	DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5
Swissprot:	Q9UQN3
Gene Accession:	BC001553
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.

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