購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗GFRA1多克隆抗體
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Background: |
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
GFRA1 |
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Immunogen: |
Synthetic peptide of human GFRA1 |
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Full name: |
GDNF family receptor alpha 1 |
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Synonyms: |
GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1 |
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SwissProt: |
P56159 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human brain and Human ovarian cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
51 kDa |
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WB Positive control: |
Rat brain tissue lysate |
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WB Recommended dilution: |
500-2000 |
